Some of the world’s premier pharmaceutical companies have drug development programs targeting NNRs, a testament to the significant opportunity in this area, and we have established ourselves as a leader. Our scientists—many of whom have been active in NNR research since the 1980s—have contributed significantly to the growth of NNR-based knowledge through extensive research, presentations and publications. Our leadership position is reflected in our extensive patent estate.

Axons and dendrites transport nerve impulses as electrical signals.

In this enlargement of the synapse, the communication point between the axon and dendrite, the electrical signal becomes a chemical signal. Targacept's molecules modulate the activity of the chemical signal at the synapse.